Senior AI Architect

  • Moderna
  • Cambridge, Massachusetts
  • Full Time

The Role

In this role, the AI Architecture Fellow will evolve and operationalize Modernas enterprise AI strategy. Youll design, build, and guide multi-cloud, agentic, and LLM-based solutions that power our next-generation R&D, manufacturing, and business systems. You will also ensure robust security, seamless data integration, and aligned processes by partnering with security, data, and business teams across the organization. Success will be measured by the number of cost-effective, secure, and scalable AI solutions that are right-sized for Moderna, delight business partners, and unlock transformative value. Reports directly to the Chief Technology and Security Officer

Youll shape the future of AI at a company transforming global health. Youll work alongside passionate scientists, technologists, security experts, data stewards, and business leaders who share your drive to push boundaries. If you thrive in a high-velocity, security-obsessed environment and believe in the power of collaboration, creativity, and humility, we want you on our team.

Heres What Youll Do

  • Define and advance Modernas AI strategy, ensuring alignment with business goals, security standards, and process requirements

  • Architect and manage scalable solutions across Google Cloud Platform (GCP), Amazon Web Services (AWS), and Microsoft Azure

  • Lead design and deployment of large language model (LLM) services and agentic capabilities, leveraging protocols such as A2A and MCP

  • Architect and enforce agentic identity and access controls using role-based, attribute-based, and Zero Trust models

  • Implement security protections against AI-specific threatsadversarial attacks, data poisoning, model theft, prompt injectionacross the data, model, and application stack

  • Evaluate, integrate, and customize third-party agentic solutions from across the wider technology landscape (Microsoft, Amazon, OpenAI, Workday, SAP, ServiceNow, etc.) to accelerate AI-driven workflows

  • Drive rigorous build-vs-buy analyses for agentic implementations, recommending when to leverage partner ecosystem solutions

  • Design and implement AI solutions requiring multi-agent orchestration, ensuring agents communicate, collaborate, and escalate appropriately

  • Partner with AI Champions, Evangelists, Developers, Enterprise, Cloud, and Security Engineers to help prioritize, prototype, iterate, and productionize secure AI solutions

  • Assist in aligning or creating business and technical processesdata flows, governance, change managementto unlock and scale AI opportunities

  • Collaborate closely with Data Architecture and Systems Data Owners to ensure tight integration, strong data governance, lineage, and quality in AI workflows

  • Operate independently as a balanced representative of both technical engineering and business partner teams, influencing stakeholders through the value of proposed solutions rather than positional authority

  • Imagine the art of the possiblethink creatively to envision bold AI innovations and translate those visions into enterprise-class, production-ready solutions

  • Define and track metrics for success, including solution cost-effectiveness, security posture, scalability, and business partner satisfaction

  • Present architectural blueprints, risk assessments, and ROI analyses to senior leadership, tailoring communications for technical and non-technical audiences

  • Mentor and coach cross-functional teams, fostering a culture of security-minded innovation, continuous learning, and humility

  • Additional duties as may be assigned from time to time

Culture and Mindsets

  • Embrace Modernas growth-and-agile mindset: dare to innovate, validate rigorously, and iterate fast

  • Lead with humility: listen actively, give credit, and learn from both successes and setbacks

  • Cultivate deep collaboration across security, data, engineering, and business teams to build trust and shared ownership

  • Influence through the strength of your ideas and the measurable value they deliver, not through positional authority

  • Imagine whats possible, challenging conventions to unlock novel solutions that delight stakeholders

  • Own outcomes end-to-end, balancing speed with quality, security, and compliance

  • Communicate transparently and succinctly, ensuring alignment at every level of the organization

Heres What Youll Need (Basic Qualifications)

  • Bachelors degree in computer science, Engineering or related field

  • Minimum of 10 years experience of hands-on architecting AI/ML solutions in large, global commercial organizations

  • Deep expertise in multi-cloud environments (GCP, AWS, Azure), including security, networking, and cost optimization

  • Proven track record with large language models and agentic frameworks, including protocols A2A and MCP

  • Demonstrated success integrating third-party AI/agentic platforms into complex IT landscapes

  • Hands-on experience designing and operating multi-agent orchestration frameworks

  • Strong background in identity and access management frameworks (RBAC, ABAC, OAuth, Zero Trust)

Heres What Youll Bring to the Table (Preferred Qualifications)

  • Advanced degree in Computer Science, Engineering or related field

  • Experience designing and implementing AI security defenses against adversarial and data integrity threats

  • Proven ability to collaborate with Data Architecture teams and Systems Data Owners on governance, metadata, and integration

  • Demonstrated ability to influence diverse stakeholders using solution value rather than title or hierarchy

  • Creative thinker with a talent for envisioning transformative AI use cases and converting big ideas into enterprise-grade implementations

  • Exceptional analytical skills with experience leading build-vs-buy evaluations for enterprise software

  • Excellent communication skills; adept at distilling complex technical, security, and process considerations into clear, concise narratives for executives

  • Experience in health sciences or life sciences environments is a plus

At Moderna, we believe that when you feel your best, you can do your best work. Thats why our US benefits and global well-being resources are designed to support youat work, at home, and everywhere in between.

  • Best-in-class healthcare coverage, plus a suite of voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Lifestyle Spending Accounts to personalize your well-being journey
  • Family planning and adoption benefits
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investment opportunities
  • Location-specific perks and extras

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Our Working Model

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

Were focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com .

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicants ability to access export-controlled information in accordance with U.S. law. Only U.S. persons (U.S. citizens, U.S. lawful permanent residents, asylees, or refugees) are currently eligible to access such information without an export license. Candidates who do not meet these criteria may still be considered, contingent on the companys ability to obtain any required export control license.

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Job ID: 489834274
Originally Posted on: 8/18/2025

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